Clinical Efficacy Testing for Cosmetics
Use tests and clinical efficacy testing play a crucial role in substantiating claims, ensuring safety, and validating efficacy for Personal Care and Medical Device products. At QACS, our clinical efficacy testing services offer a range of protocols, scientific expertise, advanced measuring equipment, and a diverse volunteer base to support cosmetic claim substantiation. Our studies adhere to optimal scientific practices and regulatory standards.
Consumer in-use tests are meticulously designed to meet manufacturer requirements, including specific instructions for application and duration. These tests rigorously evaluate cosmetic efficacy, delivering valid claims to consumers.
Trust QACS Lab for comprehensive clinical efficacy testing that guarantees the reliability and effectiveness of your cosmetic products.
Skin Testing
QACS offers skin Cosmetic Microbiome studies in the form of clinical trials to substantiate product microbiome claims. Our dedicated team offers a variety of options on skin microbiome evaluation to address your product needs. Microbiome studies, adopted to your product’s needs and budget, are provided in the form of customized protocols. At QACS we conduct Microbiome Balance and Microbiome Friendly studies.
Quorum Quenching has been proposed as a potential strategy to modulate skin microbes behavior and to promote skin health. We have developed a protocol for screening cosmetic formulations, for their ability to inhibit quorum sensing of targeted microbes such as P.acnes and S.aureus. With Quorum Quenching Analysis from QACS Lab you can assist the creation of anti-acne products by disrupting the biofilms formed by pathogenic skin microbes, making them more susceptible to immune clearance and antimicrobial agents!
Under the expert supervision of our dermatologists, we:
- Conduct Instrumental Moisture Measurements: Utilizing advanced devices such as the Moisture Meter SC and Corneometer® CM 825, we accurately measure the hydration levels of the skin.
- Statistically Interpret All Measurements: Our team employs rigorous statistical analysis to ensure meaningful and actionable insights from the data collected.
We offer a range of testing services to evaluate the hydration efficacy of cosmetic products, including:
- Short-Term Tests: Measuring skin moisture levels over a 2-hour period using the Moisture Meter SC or Corneometer® CM 825.
- Long-Term Tests: Evaluating sustained hydration effects over one week with the Moisture Meter SC or Corneometer® CM.
- Custom Moisture Tests: Tailored to meet specific research and development requirements, providing flexibility and precision.
Moisture Testing services can also be provided for Disinfectant Products
At QACS Lab, we specialize in evaluating the efficacy of cosmetic products in strengthening the skin barrier and preventing common skin issues. We conduct thorough skin barrier function assessments on a carefully selected panel of volunteers, ensuring precise and reliable results.
Under the expert supervision of our dermatologists, we perform instrumental Transepidermal Water Loss (TEWL) measurements. These measurements provide critical insights into the effectiveness of products in enhancing the skin barrier’s integrity. Our comprehensive approach includes both short-term and long-term testing, with rigorous statistical interpretation of the data.
Our TEWL testing services include:
- Short-Term Tests: Assessing water evaporation from the skin over 30 minutes using the Tewameter® TM 300.
- Long-Term Tests: Evaluating water evaporation from the skin over one week using the Tewameter® TM 300.
- Custom TEWL Tests: Tailored to meet specific research and development needs.
In addition to TEWL measurements, we conduct instrumental moisture measurements to provide a holistic view of a product’s impact on skin hydration.
By leveraging advanced imaging systems and standardized scales, QACS Lab delivers precise and reliable data on the efficacy of whitening products. Our expert dermatologists oversee every step to ensure the highest standards of scientific rigor and reliability.
To evaluate skin color and whitening efficacy, we employ the following methods:
- VISIA Complexion Analysis System: This state-of-the-art technology provides detailed imaging and analysis, allowing us to precisely measure changes in skin tone and pigmentation.
- Pantone Scale: We use the Pantone scale for standardized and consistent assessment of skin color variations.
Under the supervision of our dermatologists, we:
- Perform Clinical Evaluations: Our team conducts thorough clinical assessments to determine the effectiveness of whitening products.
- Take Before and After Photographs: High-quality photographic documentation captures the skin’s condition before and after product use.
- Provide Auto-Evaluation Reports: Compiled by a selected panel of volunteers, these reports include in-use test feedback and responses to detailed questionnaires, offering valuable insights into user experiences and perceptions.
Under the supervision of our dermatologists, we:
- Utilize VISIA Complexion Analysis System and Visioscan: For precise wrinkle and fine-line depth measurements.
- Conduct Clinical Evaluations: Comprehensive assessments of product effectiveness.
- Take Before and After Photographs: Documenting visible improvements.
- Provide Auto-Evaluation Reports: Compiled from in-use tests and volunteer questionnaires for detailed insights.
Trust QACS Lab for scientifically validated anti-wrinkle testing, ensuring accurate results and enhanced clinical efficacy testing solutions.
We evaluate the elasticity effect of cosmetic products on the skin using ElastiMeter.
Under the supervision of our dermatologists we:
- Utilize ElastiMeter: For precise measurements of skin elasticity and firmness.
- Conduct Instrumental Texture Analysis: Comprehensive assessments of skin smoothness and texture.
- Statistically Interpret All Measurements: Ensuring reliable and actionable data.
- Perform Clinical Evaluations: Thorough assessments of product performance.
- Provide Auto-Evaluation Reports: Compiled from in-use tests and detailed volunteer questionnaires, offering valuable insights.
We assess Redness and Porphyrins reduction properties of cosmetic products on the face using the VISIA Complexion Analysis System. Under the supervision of our dermatologists we:
- Measure Redness and Porphyrins: Utilizing advanced instrumental techniques.
- Statistically Interpret Data: Ensuring precise and reliable results.
- Perform Clinical Evaluations: To confirm product efficacy.
- Take Before and After Photos: Documenting visible changes.
- Provide Auto-Evaluation Reports: From in-use tests and volunteer questionnaires.
We assess the effect of cosmetic products on the secretion level of sebum. Under the supervision of our dermatologists:
- Carry Out Instrumental Sebum Measurements: Utilizing the Sebumeter® SM 815 for accurate results.
- Statistically Interpret Data: Ensuring precise and reliable sebum level analysis.
- Conduct Desquamation Tests: Using Corneofix® F 20 to evaluate skin shedding and overall skin health.
- Provide Auto-Evaluation Questionnaires: Completed by a selected panel of volunteers to gather user insights.
We assess Pores, UV and Brown spots measurements of cosmetic products on the face using the VISIA Complexion Analysis System.
Under the supervision of our Dermatologists:
- We carry out instrumental Pores-UV-Brown spots measurements.
- We statistically interpret all measurements.
- We perform clinical evaluations.
- We take before and after photographs.
- We provide auto-evaluation questionnaires answered by the selected panel of volunteers.
We substantiate the comedolytic action and non-comedogenicity of cosmetic products, particularly for acne-prone skin, utilizing advanced tools such as the Sebumeter® or Sebutape® and Dermatoscope. Under the supervision of our dermatologists, our comprehensive testing includes:
- Assessment Based on Acne-Prone Skin Criteria: Products are evaluated using specialized assessment scales tailored for acne-prone skin.
- Standardized Digital Imaging: We employ state-of-the-art digital imaging and picture comparison software to ensure precise analysis.
- Statistical Analysis: All measurements are rigorously interpreted using statistical methods to provide reliable data.
- Before and After Photography: High-quality photographs capture visible improvements before and after product usage.
Trust our clinically supervised testing services to validate the effectiveness and non-comedogenic nature of cosmetic products for acne-prone skin.
At QACS we conduct Sensory evaluation of cosmetics, household and personal care products following international standardized protocols and practices.
Focused on vision, smell and touch, sensory testing of cosmetic products can investigate sensorial properties in relation to their consumer liking and sensory profile (color, smell, rheological properties).
In QACS Lab:
- we offer documented results of sensory analysis, based on integrity and impartiality.
- our testing booths are designed according to ISO 8589:2007 and we use special sensory software for data collection and statistical analysis.
- we pay close attention to selection and implementation of the appropriate sensory methods and inclusion criteria of panelists to the studies.
A particularly useful tool for the sensory evaluation of cosmetics is the descriptive analysis method or known as Profiling. It includes the detection and quantification of the sensory attributes by expert sensory panelists. The attributes are scored with objective criteria and the results are presented in diagrams, such as spider plots.
Sensory experts, trained judges and consumers participate in the assessment of the sensorial characteristics of products. The sensory perception in terms of smell, aspect, and texture is studied and described for the optimization of new developments and evaluated in comparison to Market Leaders. Sensory testing is a powerful tool in product benchmarking.
At QACS, we conduct use tests to evaluate the clinical efficacy of cosmetic products. Volunteers use the product under normal conditions for a specified period, following criteria chosen by the study sponsor to match the target consumer profile. Our studies are supervised by trained clinical professionals, such as dermatologists, ophthalmologists, dentists, or cosmetologists, depending on the product’s target area.
We provide suggested questionnaires for volunteers to complete during and/or at the end of the study, ensuring comprehensive feedback. Trust QACS Lab for scientifically validated use tests that enhance the credibility and effectiveness of your cosmetic products.
Hair
We assess the anti-dandruff effect of cosmetic products using anti-dandruff desquamation (Corneofix® F 20).
Under the supervision of our Dermatologists we:
- Perform clinical evaluation.
- Take before and after images.
- Provide auto-evaluation questionnaires answered by the selected panel of volunteers.
Hair combing force tests from QACS assist you assess the performance of a treatment intended for hair application. You can measure Hair Combability ie the ease with which hair may be combed. This can be achieved via Hair Combing Force or Resistance to Combing tests. Hair combing force tests can be applied for conditioners, shampoos, sprays and other hair products.
At QACS we conduct Sensory evaluation of cosmetics, household and personal care products following international standardized protocols and practices.
Focused on vision, smell and touch, sensory testing of cosmetic products can investigate sensorial properties in relation to their consumer liking and sensory profile (color, smell, rheological properties).
In QACS Lab:
- we offer documented results of sensory analysis, based on integrity and impartiality.
- our testing booths are designed according to ISO 8589:2007 and we use special sensory software for data collection and statistical analysis.
- we pay close attention to selection and implementation of the appropriate sensory methods and inclusion criteria of panelists to the studies.
A particularly useful tool for the sensory evaluation of cosmetics is the descriptive analysis method or known as Profiling. It includes the detection and quantification of the sensory attributes by expert sensory panelists. The attributes are scored with objective criteria and the results are presented in diagrams, such as spider plots.
Sensory experts, trained judges and consumers participate in the assessment of the sensorial characteristics of products. The sensory perception in terms of smell, aspect, and texture is studied and described for the optimization of new developments and evaluated in comparison to Market Leaders. Sensory testing is a powerful tool in product benchmarking.
We assess the efficacy of epilating wax and measure hair growth using a dermatoscope. Under the supervision of our Dermatologists:
- We perform clinical evaluations.
- We carry out before and after assessment.
- We provide auto-evaluation questionnaires answered by the selected panel of volunteers.
At QACS, we conduct use tests to evaluate the clinical efficacy of cosmetic products. Volunteers use the product under normal conditions for a specified period, following criteria chosen by the study sponsor to match the target consumer profile. Our studies are supervised by trained clinical professionals, such as dermatologists, ophthalmologists, dentists, or cosmetologists, depending on the product’s target area.
We provide suggested questionnaires for volunteers to complete during and/or at the end of the study, ensuring comprehensive feedback. Feedback could be given on straitening, shine, wavy and other hair product claims. Trust QACS Lab for scientifically validated use tests that enhance the credibility and effectiveness of your cosmetic products.
“Reducing hair loss” or “preventing hair fall” are popular claims for cosmetics products. We assess the effect of cosmetic products on a selected panel of volunteers.
Under the supervision of our Dermatologists we:
- Perform clinical evaluation.
- Take before and after images.
- Provide auto-evaluation questionnaires answered by the selected panel of volunteers.
Breaking of hair is due to a reduction in tensile strength of hair fiber leading to hair loss. Resistance to breakage is a function of the hair cortex condition affected by dyes or stiff hairstyle choices.
At QACS we evaluate the efficacy of breaking resistance/strength hair care products using Texture Analyzer® with hair force test.
Under the supervision of our Dermatologists we:
- Perform ex vivo assessment.
- Take before and after images.
- Provide auto-evaluation questionnaires answered by a selected panel of volunteers complaint with sponsors criteria and aligned with ethical commitment.
Eyes
Clinical Efficacy Testing for Eye products.
Ophthalmological assessment of cosmetic products after an application period using a slit lamp. If the results are satisfactory, the claim “ophthalmologically tested” can be written on the label.
At QACS, we conduct use tests to evaluate the clinical efficacy of cosmetic products. Volunteers use the product under normal conditions for a specified period, following criteria chosen by the study sponsor to match the target consumer profile. Our studies are supervised by trained clinical professionals, such as dermatologists, ophthalmologists, dentists, or cosmetologists, depending on the product’s target area.
We provide suggested questionnaires for volunteers to complete during and/or at the end of the study, ensuring comprehensive feedback. Trust QACS Lab for scientifically validated use tests that enhance the credibility and effectiveness of your cosmetic products.
Oral Care
At QACS we conduct Sensory evaluation of cosmetics, household and personal care products following international standardized protocols and practices.
Focused on vision, smell and touch, sensory testing of cosmetic products can investigate sensorial properties in relation to their consumer liking and sensory profile (color, smell, rheological properties).
In QACS Lab:
- we offer documented results of sensory analysis, based on integrity and impartiality.
- our testing booths are designed according to ISO 8589:2007 and we use special sensory software for data collection and statistical analysis.
- we pay close attention to selection and implementation of the appropriate sensory methods and inclusion criteria of panelists to the studies.
A particularly useful tool for the sensory evaluation of cosmetics is the descriptive analysis method or known as Profiling. It includes the detection and quantification of the sensory attributes by expert sensory panelists. The attributes are scored with objective criteria and the results are presented in diagrams, such as spider plots.
Sensory experts, trained judges and consumers participate in the assessment of the sensorial characteristics of products. The sensory perception in terms of smell, aspect, and texture is studied and described for the optimization of new developments and evaluated in comparison to Market Leaders. Sensory testing is a powerful tool in product benchmarking.
In vivo clinical studies for oral care products evaluate safety, performance and assist you reach marketing claims. We test toothpastes, mouthwashes, whitening pens and other oral care products to substantiate claims such as whitens teeth, fresh breath, prevents plaques. Studies are conducted under the scientific supervision of dentists.
At QACS, we conduct use tests to evaluate the clinical efficacy of cosmetic products. Volunteers use the product under normal conditions for a specified period, following criteria chosen by the study sponsor to match the target consumer profile. Our studies are supervised by trained clinical professionals, such as dermatologists, ophthalmologists, dentists, or cosmetologists, depending on the product’s target area.
We provide suggested questionnaires for volunteers to complete during and/or at the end of the study, ensuring comprehensive feedback. Trust QACS Lab for scientifically validated use tests that enhance the credibility and effectiveness of your cosmetic products.
Clinical Efficacy Testing Methodology
QACS clinical efficacy testing includes
- In use tests
- Ophthalmological tests
- Dermatological tests – Patch and HRIPT tests
- standard & custom testing protocols
- pool of more than 1000 volunteers, male or female, aged 18 to 65, covering a wide range of specific characteristics (e.g. sensitive skin, comedones, oily skin, normal skin, dry skin, normal eyes, contact lens wearers etc.)
- Skin type diversity facilitates all types of cosmetic efficacy testing and enables product claims substantiation
- Test panel can be customized
Dermatologists, Ophthalmologists and Dentists provide clinical efficacy testing throughout the evaluation.
At the end of the study, a final report is delivered which includes:
- Data interpretation and statistical analysis
- Documented experts opinion
- Panelists opinion
- High-resolution images of the skin surface for marketing purposes upon request
If you are based in the EU, we offer 24-hour courier service.
To provide the highest possible quality for your products, we comply with the following ISO 9001 quality management system regulatory requirements.
For standard and custom Clinical Efficacy testing for cosmetics contact us – [email protected] – +30 210 29 34745